Greenville is the county seat and most populous city of Pitt County, North Carolina, United States. It is the principal city of the Greenville, NC Metropolitan Statistical Area, and the 12th-most populous city in North Carolina. Greenville is the health, entertainment, and educational hub of North Carolina's Tidewater and Coastal Plain. As of the 2020 census, there were 87,521 people in the city. The city has continued to see a population and economic boom with most of the growth being seen in the 20th and 21st centuries.