The Chicago Cubs (48-33) and the Houston Astros (48-33) open a 3-game series Friday. First pitch from Daikin Park is scheduled for 8:10 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Cubs vs. Astros odds and make our expert MLB picks and predictions for the best bets.

Preview the June 28 matchup between the Houston Astros and Chicago Cubs with odds over/under, game spread, betting lines and more.

It's Friday, June 27 and the Cubs (48-33) are in Houston to take on the Astros (48-33). Cade Horton is slated to take the mound for Chicago against Brandon Walter for Houston. The Cubs are 3-5 over the past eight games and coming off a 2-2 series tie with the Cardinals.

Shota Imanaga’s performance in his return made it difficult to tell how much time had passed since he pitched in a major-league game.

Shota Imanaga returned from the injured list to throw five innings of one-hit ball, lifting the Chicago Cubs to a 3-0 victory over the St. Louis Cardinals for a split of a four-game series

Chicago Cubs left-hander Shota Imanaga pitched five scoreless innings against St. Louis on Thursday in his return from a strained left hamstring that had sidelined him since May 4. Imanaga, a 31-year-old from Japan in his second season with Chicago,