SpaceX’s Starship spacecraft exploded on its test stand late Wednesday, sending a large fireball into the South Texas sky and dealing another major setback to Elon Musk’s company. It was the fourth time the company has lost a Starship spacecraft this year. In three previous test flights, the vehicle came apart or detonated during its flight.

Elon Musk’s SpaceX Starship exploded into an enormous fireball on Wednesday night during a test for an upcoming launch, in a catastrophic setback for the private space company.