Both forms are considered generally safe but may interact with certain medications. Methylcobalamin vs. Cyanocobalamin Methylcobalamin and cyanocobalamin are the two forms of vitamin B12 most ...

Cyanocobalamin is safe, and found in food additives, health supplements and the injections that doctors give patients with anemia." Gray concurred, noting that B12 has been used safely for decades.

A report by ConsumerLabs.com says cyanocobalamin, the man-made form of B12 found most often in supplements, does contain a cyanide molecule, but is still safe for consumption.

Methylcobalamin and cyanocobalamin are the two most common sources of vitamin B12. We look at their main differences and their benefits.

Once consumed, cyanocobalamin is metabolised into the active form of B12, and the cyanide is then removed in the urine. Cyanocobalamin is considered non-toxic and is generally recognised to be safe.

The FDA has approved the version of vitamin B12 called cyanocobalamin, which is found in Celsius energy drinks, as completely safe.