When the COVID-19 pandemic swept across the world in 2020, the mRNA vaccines came to the rescue of many people—but in the ...

Scientists from the University of Pennsylvania have developed an ideal “recipe” for ionizable lipids, which are essential components of lipid nanoparticles (LNPs), the molecules that underlie the ...

Researchers have cooked up a new way to improve mRNA delivery, developing an optimal “recipe” for ionizable lipids — key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 ...

Lipid nanoparticles containing acid degradable lipids transfected multiple non-liver organs after an intravenous injection and efficiently transfected brain tissue after an intracranial injection. The ...

More information: Xue, L., et al. Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery, Nature ...

Lipid-based Nanoparticles for siRNA Delivery Nanoplatforms have higher biocompatibility and lower toxicity in comparison with inorganic nanoparticles and viral vectors.

Penn Engineers have developed a Lipid Nanoparticle (LNP) that delivers mRNA theraputic to the placenta to treat pre-eclampsia in mice with human trials on the horizon.

A combination of mRNA and a new lipid nanoparticle could help heal damaged lungs, ... The life-saving mRNA COVID vaccines used unique lipid nanoparticles as the mRNA delivery system.

Genprex Collaborators Present Research on Non-Viral Approach to Diabetes Gene Therapy Using Lipid Nanoparticle Delivery System at the 2025 American Diabetes Association 85th Scientific Sessions ...

Nov 22, 2024: Researchers refine lipid nanoparticles for better mRNA therapies (Nanowerk News) Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal “recipe” for ...