To determine whether the location of this critical boundary on the human sex chromosomes—where they stop crossing over during meiosis and become X-specific or Y-specific—had been misidentified ...

In particular, it explains that humans have one fewer chromosome pair in their cells than apes, due to a mutation found in chromosome number 2 that caused two chromosomes to fuse into one.

Cytologists had been studying chromosome behavior since the late 19th century. Why did it take until 1956 to figure out the correct human chromosome number, thanks to Joe Hin Tjio and Albert Levan?

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Note the potential formation of monosomy or trisomy. Once fertilization occurs, the gamete with 24 chromosomes forms a zygote with 47 chromosomes (a trisomy with an extra copy of 1 chromosome).

Gametes are haploid cells, and each cell carries only one copy of each chromosome. These reproductive cells are produced through a type of cell division called meiosis. During meiosis, a diploid ...

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