The discovery of a novel class of peripheral tryptophan hydroxylase (TPH) inhibitors is described. This class of TPH inhibitors exhibits excellent potency in in vitro biochemical and cell-based assays ...

Because of the increasing use of psychopharmacologic drugs known to increase serotonin neurotransmission, such as SSRIs, and the increasing incidence of polypharmacy, some predict that more cases ...

The release of the “feel-good” chemicals dopamine, serotonin, endorphins, and oxytocin are tied to specific lifestyle, exercise, and dietary choices. Here’s what triggers each one.

2. Serotonin. This mood-boosting neurotransmitter was made famous by SSRI (selective serotonin reuptake inhibitor) antidepressants, which increase the brain’s serotonin levels. The most effective and ...

Catalytic enantioselective allylation with a chiral bisphosphoramide was applied to the synthesis of LY426965, a serotonin antagonist. The key step, addition of a 3,3-disubstituted ...

Background and aims: The mechanisms underlying intestinal secretion in rotavirus diarrhoea remain to be established. We previously reported that rotavirus evokes intestinal fluid and electrolyte ...

This Nantucket Manse's Shades of Blue, Yellow, and Red Offer an Instant Serotonin Boost. Madoline Markham Koonce. June 12, 2025 at 9:00 AM. Copied; ...

A new study published in Cell Metabolism has found that intermittent fasting enhances sexual behavior in aging male mice—not by improving sperm quality or hormone levels, but by shifting brain ...

Serotonin is found not only in animals, but also in fungi and plants, including fruits and vegetables. This text uses material from Wikipedia, licensed under CC BY-SA. Phys.org. Daily science news ...

Adulting is, more often than not, a masterclass in navigating the mundane. Between the endless to-do lists, the slightly-too-loud hum of the office fridge, and the existential dread that sometimes ...